Brian Kopell, MD (co-chair)

Salim Hayek, MD PhD (co-chair)

Lawrence Poree, MD PhD
Nathaniel Katz, PhD
John Markman, MD
Richard North, MD

Rod Taylor, PhD

Sam Eldabe, MB ChB FRCA FFPMRCA

Steve Falowski, MD 

Vibhor Krishna, MD SM

The Clinical Trial Committee of IoN has been engaged in producing publications that guide future neuromodulation studies with a first focus on spinal cord stimulation (SCS). Historically, neuromodulation studies have been hindered by several factors including difficulty of blinding participants, cost, industry sponsorship, lack of appropriate controls… To address these issues, NANS/IoN collaborated with the International Neuromodulation Society (INS) and the Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT) to generate two documents. The first manuscript focused on research methodologies for SCS studies, by systematically reviewing published SCS prospective studies. The second manuscript expanded on research considerations in designing future studies involving spinal cord stimulation.

Duarte, R.V. et al., 2020: Randomized Placebo‐/Sham‐Controlled Trials of Spinal Cord Stimulation: A Systematic Review and Methodological Appraisal. Neuromodulation. doi:10.1111/ner.13018

Next, the Clinical Committee of IoN will explore design, costs and barriers of prospective studies examining efficacy of neuromodulation approaches compared to other standard therapies.