Brian Kopell, MD (co-chair)

Salim Hayek, MD PhD (co-chair)

Lawrence Poree, MD PhD
Nathaniel Katz, PhD
John Markman, MD
Richard North, MD

Rod Taylor, PhD

Sam Eldabe, MB ChB FRCA FFPMRCA

Steve Falowski, MD 

Vibhor Krishna, MD SM

The Clinical Trial Committee of IoN has been engaged in producing publications that guide future neuromodulation studies, focusing first on spinal cord stimulation (SCS). Historically, neuromodulation studies have been hindered by several factors including difficulty of blinding participants, cost, industry sponsorship, lack of appropriate controls… To address these issues, NANS/IoN has collaborated with the International Neuromodulation Society (INS) and the Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT), and several publications have resulted. The first three systematically reviewed and analyzed published SCS prospective studies, their reporting quality, and the use of sham and placebo controls. The fourth and most recent manuscript expanded on research considerations in designing future SCS studies and set forth detailed recommendations. 

Duarte, R.V. et al., 2020: Randomized Placebo‐/Sham‐Controlled Trials of Spinal Cord Stimulation: A Systematic Review and Methodological Appraisal. Neuromodulation. doi:10.1111/ner.13018